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A0156

Sigma-Aldrich

N-(4-Aminobutyl)-N-ethylisoluminol

≥90%, powder

Synonym(s):

4-(N1-Ethyl-4-aminobutylamino)phthalic hydrazide, 6-[N-(4-Aminobutyl)-N-ethylamino]-2,3-dihydro-1,4-phthalazinedione, ABEI

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About This Item

Empirical Formula (Hill Notation):
C14H20N4O2
CAS Number:
66612-29-1
Molecular Weight:
276.33
Beilstein:
920895
MDL number:
MFCD00010559
UNSPSC Code:
12352204
PubChem Substance ID:
24890404
NACRES:
NA.83
Pricing and availability is not currently available.

Product Name

N-(4-Aminobutyl)-N-ethylisoluminol, ≥90%

Assay

≥90%

form

powder

mp

259-260 °C (lit.)

solubility

glacial acetic acid: 50 mg/mL, clear, colorless to yellow

storage temp.

2-8°C

SMILES string

CCN(CCCCN)c1ccc2C(=O)NNC(=O)c2c1

InChI

1S/C14H20N4O2/c1-2-18(8-4-3-7-15)10-5-6-11-12(9-10)14(20)17-16-13(11)19/h5-6,9H,2-4,7-8,15H2,1H3,(H,16,19)(H,17,20)

InChI key

LEOJISUPFSWNMA-UHFFFAOYSA-N

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Features and Benefits

Efficient chemiluminescent NH2-coupling reagent for detection of a wide variety of proteins down to the picomole range.

Other Notes

Reportedly, the use of this material in chemiluminescent assays has distinct advantages over conventional radioimmunoassay.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF5562V
0000281409
0000271167
0000260371
0000252802

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F Kohen et al.
Steroids, 38(1), 73-88 (1981-07-01)
A solid-phase immunoassay procedure for the determination of progesterone in human plasma is described, which utilizes chemiluminescence as the end-point. A progesterone-isoluminol conjugate serves as the chemiluminescent marker. An IgG fraction of antiserum to progesterone-11 alpha-hemisuccinate bovine serum albumin is
Ying Chai et al.
Analytica chimica acta, 715, 86-92 (2012-01-17)
An electrochemiluminescence (ECL) biosensor for simultaneous detection of adenosine and thrombin in one sample based on bifunctional aptamer and N-(aminobutyl)-N-(ethylisoluminol) functionalized gold nanoparticles (ABEI-AuNPs) was developed. A streptavidin coated gold nanoparticles modified electrode was utilized to immobilize biotinylated bifunctional aptamer
Dayong Tian et al.
Chemical communications (Cambridge, England), 47(17), 4959-4961 (2011-03-25)
A novel strategy for the synthesis of CF-AuNMs by reducing HAuCl(4) with ABEI in aqueous solution at room temperature is reported. No additional stabilizing and reducing reagents are needed, and various morphologies of CF-AuNMs can be obtained. It could be
Zian Lin et al.
Journal of chromatography. A, 1170(1-2), 118-121 (2007-10-02)
A simple and convenient end-column chemiluminescence (CL) detection coupled to pressurized capillary electrochromatography (pCEC) was described. Luminol and N-(4-aminobutyl)-N-ethylisoluminol (ABEI) were adopted as mode compounds to evaluate the feasibility of end-column reactor. Detailed analysis of ABEI revealed that the high
Jialing Chen et al.
Clinica chimica acta; international journal of clinical chemistry, 488, 143-149 (2018-11-11)
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a novel inflammatory biomarker, which is useful as an adjunct identification tool for cardiovascular disease. However, the important limitation of the conventional enzyme-linked immunosorbent assay (PLAC ELISA) for Lp-PLA2 assay is its relatively low sensitivity
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