233152

Dithioerythritol

A protective agent for SH groups.

• Synonym(s): Dithioerythritol, Cleland’s Other Reagent, DTE
• Empirical Formula (Hill Notation): C₄H₁₀O₂S₂
• CAS Number: 6892-68-8
• Molecular Weight: 154.25
• MDL number: MFCD00063750
• UNSPSC Code: 12161504
• NACRES: NA.25

Properties

• Quality Level: 100
• Assay: ≥98% (titration)
• form: solid
• reaction suitability: reagent type: reductant
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: <1% disulfides (UV)
• color: white
• pH: 4.5-6.5 (25 °C, 15.4 g/L)
• solubility: water: 50 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+
• InChI key: VHJLVAABSRFDPM-ZXZARUISSA-N

Description

General description

A protective agent for SH groups.

Water-soluble, cell-permeable protective reagent for sulfhydryl groups. Maintains monothiols in the reduced state and reduces disulfides quantitatively. Protects protein sulfhydryls and restores enzyme activity lost by the oxidation of sulfhydryl groups in vitro.

Packaging

Packaged under inert gas

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 2 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H412
• Precautionary Statements: P264 - P270 - P273 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3