1121005

Chlorothiazide

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• Empirical Formula (Hill Notation): C₇H₆ClN₃O₄S₂
• CAS Number: 58-94-6
• Molecular Weight: 295.72
• NACRES: NA.24
• PubChem Substance ID: 329749327
• UNSPSC Code: 41116107
• MDL number: MFCD00058576

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: chlorothiazide
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: O=S(C1=C2C=C(Cl)C(S(N)(=O)=O)=C1)(NC=N2)=O
• InChI: 1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-3H,(H,10,11)(H2,9,12,13)
• InChI key: JBMKAUGHUNFTOL-UHFFFAOYSA-N
• Gene Information: human ... SLC12A3(6559)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorothiazide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Benazepril Hydrochloride and Hydrochlorothiazide Tablets
• Bisoprolol Fumarate and Hydrochlorothiazide Tablets
• Candesartan Cilexetil and Hydrochlorothiazide Tablets
• Chlorothiazide
• Chlorothiazide Compounded Oral Suspension
• Chlorothiazide Oral Suspension
• Chlorothiazide Sodium for Injection

One of the first in the thiazide class of diuretics.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H317,H334
• pcodes: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable