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Merck

SML3294

SGC-CK2-1N

≥98% (HPLC)

Synonym(s):

N-(5-((3-Cyano-7-(cyclopropyl(methyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)(methyl)amino)-2-methylphenyl)cyclopropanecarboxamide, SGC-CK2-1 inactive control, SGC-CK2-1 negative control

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About This Item

Empirical Formula (Hill Notation):
C23H25N7O
CAS Number:
Molecular Weight:
415.49
NACRES:
NA.32
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

2-8°C

Biochem/physiol Actions

Inactive structure analog of and the negative control for the potent and highly selective casein 2 (CK2, CKII) inhibitor SGC-CK2-1.
SGC-CK2-1N is an inactive structure analog of and the recommended negative control for the potent and highly selective casein 2 (CK2, CKII) inhibitor SGC-CK2-1 (CK2α/CK2α’ IC50 >10 μM with SGC-CK2-1N vs IC50 = 4.2/2.3 nM with SGC-CK2-1 by cell-free enzyme assay).


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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