S5076

SF-22

≥98% (HPLC)

• Synonym(s): N-[1,1′-Biphenyl]-2-yl-3-[[(2,5-dimethylphenyl)amino]sulfonyl]-4-methyl-benzamide, SID 17413034
• Empirical Formula (Hill Notation): C₂₈H₂₆N₂O₃S
• CAS Number: 824981-55-7
• Molecular Weight: 470.58
• NACRES: NA.77
• PubChem Substance ID: 329824449
• UNSPSC Code: 12352200
• MDL number: MFCD06623281
• Assay: ≥98% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• solubility: DMSO: 26 mg/mL
• storage temp.: room temp
• SMILES string: Cc1ccc(C)c(NS(=O)(=O)c2cc(ccc2C)C(=O)Nc3ccccc3-c4ccccc4)c1
• InChI: 1S/C28H26N2O3S/c1-19-13-14-20(2)26(17-19)30-34(32,33)27-18-23(16-15-21(27)3)28(31)29-25-12-8-7-11-24(25)22-9-5-4-6-10-22/h4-18,30H,1-3H3,(H,29,31)
• InChI key: BWWPVIRXNOWQSI-UHFFFAOYSA-N

Description

Application

SF-22 may be used in NPY Y2 receptor-mediated studies.

Biochem/physiol Actions

Radioligand studies reveal that SF-22 also targets 5-HT_2B and 5-HT₆ serotonin receptors and dopamine transporter.¹

SF-22 is a potent, selective NPY Y2 receptor antagonist; highly brain-penetrant

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable