Key Documents

Peptide YY human

Name: Peptide YY human
Brand: SIGMA

≥97% (HPLC), synthetic

Synonym(s):

PYY, Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH₂

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About This Item

Empirical Formula (Hill Notation):

C₁₉₄H₂₉₅N₅₅O₅₇

CAS Number:

118997-30-1

Molecular Weight:

4309.75

UNSPSC Code:

51111800

NACRES:

NA.32

MDL number:

MFCD00081843

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Properties

biological source

synthetic

Quality Segment

200

assay

≥97% (HPLC)

form

solid

UniProt accession no.

P10082

storage temp.

−20°C

Gene Information

human ... PYY(5697)

Description

General description

Human peptide YY (PYY) is secreted by mucosal L cells in the distal ileum, colon and rectum. It consists of 36 amino acids. The gene encoding PYY is localized on human chromosome 17q21.1.

Application

Peptide YY human has been used as a supplement in Roswell Park Memorial Institute medium (RPMI medium) to culture pancreatic duct-derived cells.

Biochem/physiol Actions

Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.

Inhibits secretin and cholecystokinin-stimulated pancreatic secretion;endogenous nonselective agonist at NPY receptors.

Human peptide YY (PYY) has a role in food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes. PYY also has a role in energy homeostasis.

Other Notes

Lyophilized from 0.1% TFA in H2O

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This Item	C9781	G8022	492042
Sigma-Aldrich P1306 Peptide YY human	Sigma-Aldrich C9781 Tyr-C-Peptide human	Sigma-Aldrich G8022 Gastrin Releasing Peptide human	Sigma-Aldrich 492042 Nrf2 Activator III, TAT-14 Peptide
description ≥97% (HPLC), synthetic	description ≥95% (HPLC)	description ≥97% (HPLC)	description The Nrf2 Activator III, TAT-14 Peptide modulates the biological activity of Nrf2. This small molecule/inhibitor is primarily used for Biochemicals applications.
assay ≥97% (HPLC)	assay ≥95% (HPLC)	assay ≥97% (HPLC)	assay ≥95% (HPLC)
biological source synthetic	biological source -	biological source -	biological source -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
form solid	form powder	form -	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
Gene Information human ... PYY(5697)	Gene Information human ... INS(3630)	Gene Information human ... GRP(2922)	Gene Information -

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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