G3907
Glutathione−Agarose
set of 3 pre-packed columns (2.5 ml each), (1:1 suspension in a 0.5 M NaCl + 20% ethanol solution)
Synonym(s):
GSH-agarose, S-linked glutathione agarose
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About This Item
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Quality Level
form
(1:1 suspension in a 0.5 M NaCl + 20% ethanol solution)
analyte chemical class(es)
proteins (GST)
packaging
set of 3 pre-packed columns (2.5 ml each)
technique(s)
immunoprecipitation (IP): suitable
protein purification: suitable
matrix
cross-linked 4% beaded agarose
storage temp.
2-8°C
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General description
The resin in these columns consists of glutathione attached through the sulfur to epoxy activated, 4% cross-linked beaded agarose resulting in a 12 atom spacer.
Application
Affinity chromatography using glutathione-agarose permits rapid, mild, non-denaturing and highly selective purification of glutathione binding enzymes such as glutathione-S-transferase, glutathione peroxidase, and glyoxalase I.
The product was used in the design, synthesis and biological evaluation of new tryptamine and tetrahydro-β-carboline-based selective inhibitors of CDK4. It was also used to study Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1.
The product was used in the design, synthesis and biological evaluation of new tryptamine and tetrahydro-β-carboline-based selective inhibitors of CDK4. It was also used to study Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1.
Affinity chromatography using glutathione-agarose permits rapid, mild, non-denaturing and highly selective purification of proteins containing glutathione binding sequences, such as Glutathione S-Transferase (GST), glutathione peroxidase and glyoxalase I.
Linkage
Suspension of Product No. G 4510
Physical form
1:1 suspension in a 0.5 M NaCl + 20% ethanol solutionl
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
180.1 °F
Flash Point(C)
82.3 °C
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