Based on the predominating linoleoyl fatty acid residues in this product the approximate molecular weight is 1500.
C0563
Cardiolipin sodium salt from bovine heart
≥97% (TLC), lyophilized powder
Synonym(s):
Diphosphatidylglycerol
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About This Item
Pricing and availability is not currently available.
biological source
bovine heart
Quality Segment
assay
≥97% (TLC)
form
lyophilized powder
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
General description
Cardiolipin is localized in the inner membrane of mitochondria. It contains 18 carbon atoms, 3-phosphatidyl groups connected via a glycerol bridge. Cardiolipin is an important component of ATP synthase enzyme.
Application
Cardiolipin sodium salt from bovine heart has been used:
- as a phospholipid standard in thin layer chromatography for the quantification of total mitochondrial lipids of Neurospora crassa(89)
- as an internal standard in reverse phase high performance liquid chromatography (RP-HPLC) for quantification of bacterial lipid extracts(90)
- as an antigen to evaluate IgM reaction in systemic lupus erythematosus (SLE) patients(91)
Biochem/physiol Actions
Cardiolipin is a mitochondrial phospholipid that is found in mammalian tissues in low concentrations. It is often a membrane component. Inhibits cell attachment of fibronectin, vitronectin and Type I collagen.
Packaging
packaged under argon
1 of 1
This Item | ||
|---|---|---|
| assay ≥97% (TLC) | assay ≥97% (TLC) | assay >99% (TLC) |
| biological source bovine heart | biological source bovine heart | biological source - |
| shipped in ambient | shipped in dry ice | shipped in dry ice |
| form lyophilized powder | form liquid | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 300 | Quality Level - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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What is the Molecular weight of Cardiolipin sodium salt from bovine heart C0563 LOT SLCC2621?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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According to your COA for item C0563, Cardiolipin protein, the purity was tested by TLC; what are the specific test methods and experimental conditions?
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This product is classified at an MQ 200 level. We are unable to provide the analytical method for products classified below an MQ 400. However, general conditions may be shared.
Sample Concentration - 50 mg/ml
Solvent - Chloroform
Detection - Stahl's 214
Markers - Linoleic acid and Linoleic acid methyl esterHelpful?
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