Levofloxacin is only sparingly soluble in water. It is freely soluble in glacial acetic acid and chloroform.
28266
Levofloxacin
98.0-102.0% anhydrous basis (HPLC)
Synonym(s):
Levofloxacin Anhydrous, (−)-Ofloxacin
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About This Item
Empirical Formula (Hill Notation):
C18H20FN3O4
CAS Number:
Molecular Weight:
361.37
Beilstein:
7327015
MDL number:
UNSPSC Code:
51102829
PubChem Substance ID:
NACRES:
NA.85
Pricing and availability is not currently available.
Recommended Products
biological source
synthetic
Quality Level
Assay
98.0-102.0% anhydrous basis (HPLC)
form
powder or crystals
color
light yellow-white to yellow-white
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
Mode of action
enzyme | inhibits
SMILES string
OC(C(C1=O)=CN2C(C1=CC(F)=C3N4CCN(C)CC4)=C3OC[C@@H]2C)=O
InChI
1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
InChI key
GSDSWSVVBLHKDQ-JTQLQIEISA-N
Gene Information
human ... KCNH1(3756)
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Application
Biochem/physiol Actions
Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, [6] thereby inhibiting cell division.
Packaging
10mg, 1g, 10g
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1A - Skin Sens. 1A
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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To determine the steady-state plasma, epithelial lining fluid (ELF), and alveolar macrophage (AM) concentrations of levofloxacin and ciprofloxacin. Multiple-dose, open-label, randomized pharmacokinetic study. Thirty-six healthy, nonsmoking adult subjects were randomized either to oral levofloxacin, 500 or 750 mg once daily
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Is Levofloxacin 28266 soluble in water?
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