137259

PIPES disodium salt

EMPROVE^® EVOLVE

• Synonym(s): PIPES disodium salt, 1,4-Piperazinediethanesulfonic acid disodium salt, Piperazine-1,4-bis(2-ethanesulfonic acid) disodium salt
• Empirical Formula (Hill Notation): C₈H₁₆N₂Na₂O₆S₂
• CAS Number: 76836-02-7
• Molecular Weight: 346.33
• UNSPSC Code: 12352200
• Beilstein/REAXYS Number: 9453872
• MDL number: MFCD00064349

Properties

• biological source: synthetic
• Quality Segment: 400
• product line: EMPROVE^® EVOLVE
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: Endotoxin and microbial; tested
• pH: 6.1-7.5
• useful pH range: 6.1-7.5
• pKa (25 °C): 6.8
• pKa: 6.8
• suitability: suitable for manufacturing use
• foreign activity: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• storage temp.: 2-30°C
• SMILES string: [Na+].[Na+].[O-]S(=O)(=O)CCN1CCN(CC1)CCS([O-])(=O)=O
• InChI: 1S/C8H18N2O6S2.2Na/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16;;/h1-8H2,(H,11,12,13)(H,14,15,16);;/q;2*+1/p-2
• InChI key: GMHSTJRPSVFLMT-UHFFFAOYSA-L

Description

Application

PIPES Disodium is the sodium salt form of PIPES and is a biological buffer often referred to as a “Good′s” buffer. The pKa of PIPES is 6.8 which makes it ideal for biological applications at physiological conditions. PIPES Disodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.PIPES Disodium can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for cell culture and diagnostic reagent production.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable