Key Documents

Betamethasone

Name: Betamethasone
Brand: SIAL

VETRANAL^®, analytical standard

Synonym(s):

9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₂₉FO₅

CAS Number:

378-44-9

Molecular Weight:

392.46

NACRES:

NA.24

PubChem Substance ID:

329754860

UNSPSC Code:

41116107

EC Number:

206-825-4

MDL number:

MFCD00062969

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Properties

grade

analytical standard

Quality Segment

100

description

free compound

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

235-237 °C (lit.)

application(s)

clinical testing

format

neat

SMILES string

[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChI key

UREBDLICKHMUKA-DVTGEIKXSA-N

Gene Information

human ... NR3C1(2908)

Description

Application

Betamethasone may be used as an analytical reference standard for the determination of the analyte in excreta of treated animals, bovine, porcine and chicken muscles and food commodities by various chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item	PHR1398	B7005	46074
Supelco 34166 Betamethasone	Supelco PHR1398 Betamethasone	Sigma-Aldrich B7005 Betamethasone	Supelco 46074 Betamethasone 17-valerate
description VETRANAL^®, analytical standard	description Pharmaceutical Secondary Standard; Certified Reference Material	description ≥98%	description VETRANAL^®, analytical standard
grade analytical standard	grade pharmaceutical secondary standard, certified reference material	grade -	grade analytical standard
format neat	format neat	format -	format neat
mp 235-237 °C (lit.)	mp 235-237 °C (lit.)	mp 235-237 °C (lit.)	mp -
Quality Level 100	Quality Level 300	Quality Level 100	Quality Level 200
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) gas chromatography (GC): suitable, HPLC: suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable
Gene Information human ... NR3C1(2908)	Gene Information human ... NR3C1(2908)	Gene Information human ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908) mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Tnf(21926) rat ... Ar(24208), Nr3c1(24413), Tnf(24835)	Gene Information -

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Pictograms

GHS08

Signal Word

Danger

Hazard Codes

H360FD,H373

Precautionary Statements

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B - STOT RE 2

Target Organs

Liver,Kidney,Endocrine system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

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