MAB858-2
Anti-RSV Antibody, glycoprotein, all type A, B strains, clone 131-2G
clone 131-2G, from mouse
Synonym(s):
RSV
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
131-2G, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunofluorescence: suitable
isotype
IgG1κ
shipped in
wet ice
General description
RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.
Specificity
Glycoprotein, 89 kD. Recognizes both A and B strains.
Immunogen
A2
Epitope: some type B strains
Application
Detect Respiratory Syncytial Virus using this Anti-RSV Antibody, glycoprotein, all type A, B strains, clone 131-2G validated for use in ELISA & IF.
ELISA
Indirect Immunofluorescence (fresh frozen tissue sections)
Final working dilutions must be determined by end user.
Indirect Immunofluorescence (fresh frozen tissue sections)
Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
Physical form
Format: Purified
Purified immunoglobulin. 1 mg/mL in 0.02M PB with 0.25M NaCl, pH=7.6 containing 0.1% sodium azide.
Storage and Stability
Maintain at 2 to 8° C in aliquots for up to 12 months after date of receipt. Do not store in diluted format.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Exploratory Spatial Analysis of in vitro Respiratory Syncytial Virus Co-infections.
Simeonov, I; Gong, X; Kim, O; Poss, M; Chiaromonte, F; Fricks, J
Viruses null
Jorge C G Blanco et al.
Viruses, 15(6) (2023-06-28)
Respiratory syncytial virus (RSV) is a significant threat to elderly populations and repeated infections that occur throughout life are poorly protective. To assess the role of prior RSV infections as well as elderly immune senescence on vaccine efficacy, we compared
Laura L A van Dijk et al.
Cellular and molecular life sciences : CMLS, 81(1), 267-267 (2024-06-17)
Neutralizing antibodies are considered a correlate of protection against severe human respiratory syncytial virus (HRSV) disease. Currently, HRSV neutralization assays are performed on immortalized cell lines like Vero or A549 cells. It is known that assays on these cell lines
Myra N Widjojoatmodjo et al.
Virology journal, 7, 114-114 (2010-06-08)
Respiratory syncytial virus (RSV) is a primary cause of serious lower respiratory tract illness for which there is still no safe and effective vaccine available. Using reverse genetics, recombinant (r)RSV and an rRSV lacking the G gene (DeltaG) were constructed
B Cortjens et al.
Journal of virology, 91(10) (2017-03-10)
Respiratory syncytial virus (RSV) causes severe respiratory disease in young children. Antibodies specific for the RSV prefusion F protein have guided RSV vaccine research, and in human serum, these antibodies contribute to >90% of the neutralization response; however, detailed insight
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