855475P

12:0 Lyso PC

1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

• Synonym(s): 1-dodecanoyl-sn-glycero-3-phosphocholine; PC(12:0/0:0)
• Empirical Formula (Hill Notation): C₂₀H₄₂NO₇P
• CAS Number: 20559-18-6
• Molecular Weight: 439.52
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
• form: powder
• packaging: pkg of 1 × 200 mg (855475P-200mg); pkg of 1 × 25 mg (855475P-25mg); pkg of 1 × 500 mg (855475P-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 855475P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCC)=O
• InChI: 1S/C20H42NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3/t19-/m1/s1
• InChI key: BWKILASWCLJPBO-LJQANCHMSA-N

Description

General description

Lyso-phosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response. It has a choline group at its polar head. Lysophosphatidylcholine (Lyso-PC) is a component of blood plasma, vascular tissue and lipoproteins.

Application

12:0 Lyso PC has been used to study its neuritogenic activity and the applications of exogenous lipids.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) alters various functions in different cell-types, like endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC activates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.

Packaging

20 mL Clear Glass Screw Cap Vial (855475P-500mg)

5 mL Amber Glass Screw Cap Vial (855475P-200mg)

5 mL Amber Glass Screw Cap Vial (855475P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable