547352

mono-tert-Butyl succinate

97%

• Linear Formula: (CH₃)₃OCO(CH₂)₂CO₂H
• CAS Number: 15026-17-2
• Molecular Weight: 174.19
• MDL number: MFCD00273441
• UNSPSC Code: 12352100
• PubChem Substance ID: 24878932
• NACRES: NA.22

Properties

• Assay: 97%
• mp: 51-54 °C (lit.)
• functional group: carboxylic acid; ester
• SMILES string: CC(C)(C)OC(=O)CCC(O)=O
• InChI: 1S/C8H14O4/c1-8(2,3)12-7(11)5-4-6(9)10/h4-5H2,1-3H3,(H,9,10)
• InChI key: PCOCFIOYWNCGBM-UHFFFAOYSA-N

Description

General description

mono-tert-Butyl succinate can be prepared by refluxing a mixture of succinic anhydride and N-hydroxyl succinimide in the presence of dimethylaminopyridine and triethylamine in tert-butanol and toluene.

Application

mono-tert-Butyl succinate may be used in the preparation of:

• N-succinyl-L,L-diaminopimelic acid (SDAP)
• H3K9TSu (histone H3 lysine 9 thiosuccinyl) peptide
• tert-butyl 4-oxo-4-(4-tritylpiperazin-1-yl)butanoate

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves