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214515

Sigma-Aldrich

Chromotrope FB

Dye content 50 %

Synonym(s):

Acid Red 14, Disodium 4-hydroxy-3-[(4-sulfo-1-naphthalenyl)azo]-1-naphthalenesulfonate, Mordant Blue 79

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About This Item

Empirical Formula (Hill Notation):
C20H12N2Na2O7S2
CAS Number:
Molecular Weight:
502.43
Colour Index Number:
14720
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

powder

composition

Dye content, 50%

mp

275 °C

λmax

383 nm
515 nm (2nd)

ε (extinction coefficient)

≥14500 at 513-519 nm in H2O at 0.03 g/L
≥33000 at 214-220 nm in H2O at 0.03 g/L
≥9000 at 320-326 nm in H2O at 0.03 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].Oc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(c4ccccc34)S([O-])(=O)=O

InChI

1S/C20H14N2O7S2.2Na/c23-20-15-8-4-3-7-14(15)19(31(27,28)29)11-17(20)22-21-16-9-10-18(30(24,25)26)13-6-2-1-5-12(13)16;;/h1-11,23H,(H,24,25,26)(H,27,28,29);;/q;2*+1/p-2/b22-21+;;

InChI key

YSVBPNGJESBVRM-ZPZFBZIMSA-L

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Application

Chromotrope FB has been used in indirect competitive CLIA (icCLIA) to detect its presence in foods.

Biochem/physiol Actions

Chromotrope FB, also known as acid red 14 (AR14), is a bright orange-red powder. It belongs to the class of monoazides. Chromotrope FB efficiently stains fatty substances and is also used to dye food and medicines.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

>437.0 °F

Flash Point(C)

> 225 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wayne Luallen
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Handbook of Microscopy (2013)
J C Phillips et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 25(12), 927-935 (1987-12-01)
The absorption, metabolism and excretion of 14C-labelled carmoisine has been studied in the rat, mouse and guinea-pig. Following administration of a single oral dose of either 0.5 or 50 mg/kg body weight, substantially all of the dose was recovered in
A sensitive chemiluminescent immunoassay to detect Chromotrope FB (Chr FB) in foods
Xu K
Talanta, 164, 341-347 (2017)
M C Sweatman et al.
Clinical allergy, 16(4), 331-338 (1986-07-01)
We report the case of an 8.5-year-old girl with oro-facial granulomatosis associated with clinical atopy, in whom relapse of her granulomatous disorder was shown to be related to exposure to specific food additives, viz. carmoisine, sunset yellow and monosodium glutamate.

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