194530

Hexanoic anhydride

97%

• Synonym(s): Caproic anhydride
• Linear Formula: [CH₃(CH₂)₄CO]₂O
• CAS Number: 2051-49-2
• Molecular Weight: 214.30
• Beilstein: 1776561
• EC Number: 218-121-4
• MDL number: MFCD00009509
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851658
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• refractive index: n20/D 1.428 (lit.)
• bp: 246-248 °C (lit.)
• density: 0.928 g/mL at 20 °C (lit.)
• functional group: anhydride; ester
• SMILES string: CCCCCC(=O)OC(=O)CCCCC
• InChI: 1S/C12H22O3/c1-3-5-7-9-11(13)15-12(14)10-8-6-4-2/h3-10H2,1-2H3
• InChI key: PKHMTIRCAFTBDS-UHFFFAOYSA-N

Description

Application

Hexanoic anhydride was used in:

• green synthesis of esters of acyclovir (acyclovir prodrugs)
• preparation of hexanoyl-modified chitosan nanoparticles
• preparation of chitosan-based polymeric surfactants via N-acylation of chitosans

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves