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Key Documents

177377

Sigma-Aldrich

Diphenylcyclopropenone

98%

Synonym(s):

DPC

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About This Item

Empirical Formula (Hill Notation):
C15H10O
CAS Number:
Molecular Weight:
206.24
Beilstein:
608049
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

mp

118-122 °C (lit.)

SMILES string

O=C1C(c2ccccc2)=C1c3ccccc3

InChI

1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H

InChI key

HCIBTBXNLVOFER-UHFFFAOYSA-N

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General description

Diphenylcyclopropenone is a potent hapten. Its vibration frequency has been evaluated.

Application

Diphenylcyclopropenone was used in topical immunotherapy.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Valerio Tabacchini et al.
Physics in medicine and biology, 60(14), 5513-5525 (2015-07-03)
Gamma-ray detectors based on bright monolithic scintillation crystals coupled to pixelated photodetectors are currently being considered for several applications in the medical imaging field. In a typical monolithic detector, both the light intensity and the time of arrival of the
Frank Martiniuk et al.
Journal of drugs in dermatology : JDD, 9(11), 1368-1372 (2010-11-11)
The authors provide an update on a previously reported patient with in-transit metastatic melanoma of the scalp treated with topical diphencyprone (DPCP). Molecular studies implicate the thymus-derived TH17 lymphocyte subset in a remarkable immunotherapeutic regression. The authors performed RT-PCR of
Leena M Koulu et al.
The Journal of investigative dermatology, 130(11), 2578-2582 (2010-07-09)
Polymorphic light eruption (PLE) is a common skin disorder provoked by exposure to UVR. Its clinical symptoms resemble those of a contact allergic reaction. PLE is generally considered a T-cell-mediated autoimmune reaction toward a yet unidentified antigen formed in UVR-exposed
Marie T Vennegaard et al.
Contact dermatitis, 67(5), 298-305 (2012-05-19)
MicroRNAs are short, endogenous RNA molecules that can bind to parts of target mRNAs, thus inhibiting their translation and causing accelerated turnover or degradation of transcripts, thereby regulating gene expression. Several microRNAs have been found to be upregulated in atopic
Adam D Harper Smith et al.
Brain, behavior, and immunity, 25(6), 1136-1142 (2011-03-03)
Little is known about the influence of exercise on induction and elicitation phases of in vivo immunity in humans. We used experimental contact-hypersensitivity, a clinically relevant in vivo measure of T cell-mediated immunity, to investigate the effects of exercise on

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