Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

163457

Sigma-Aldrich

(+)-Dimethyl L-tartrate

99%

Synonym(s):

L-(+)-Tartaric acid dimethyl ester

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
[-CH(OH)CO2CH3]2
CAS Number:
608-68-4
Molecular Weight:
178.14
Beilstein:
1726256
EC Number:
210-166-8
MDL number:
MFCD00064437
UNSPSC Code:
12352108
PubChem Substance ID:
24849749
NACRES:
NA.22

Quality Level

200

Assay

99%

form

solid

optical activity

[α]22/D +21°, c = 2.5 in H2O

optical purity

ee: ≥99% (GLC)

bp

163 °C/23 mmHg (lit.)

mp

57-60 °C (dec.) (lit.)

density

1.238 g/mL at 25 °C (lit.)

SMILES string

COC(=O)[C@H](O)[C@@H](O)C(=O)OC

InChI

1S/C6H10O6/c1-11-5(9)3(7)4(8)6(10)12-2/h3-4,7-8H,1-2H3/t3-,4-/m1/s1

InChI key

PVRATXCXJDHJJN-QWWZWVQMSA-N

Looking for similar products? Visit Product Comparison Guide

Application

(+)-Dimethyl L-tartrate can react with sulfur tetrafluoride to form dimethyl meso-2,3-difluorosuccinate.
It may be used in the synthesis of the following chiral ligands for use in asymmetric synthesis:
  • (2R, 3R)-1,4-dimethoxy-1,1,4,4-tetraphenyl-2,3-butanediol
  • (-)-(4S,5R)-4-(2-pyridyl)-5-(diphenylphosphino)methyl-2,2-dimethyl-1,3-dioxolane (PYDIPHOS)
  • (4R,5R)-α,α,α′,α′-2,2-hexaphenyl-4,5-dimethanol-1,3-dioxolane

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis of (2R, 3R)-1, 4-dimethoxy-1, 1, 4, 4-tetraphenyl-2, 3-butanediol: A new C2-symmetric vicinal diol from dimethyl L-tartrate.
Nakayama K and Rainier JD.
Tetrahedron, 46(12), 4165-4170 (1990)
(-)-(4S, 5R)-4-(2-pyridyl)-5-(diphenylphosphino) methyl-2, 2-dimethyl-1, 3-dioxolane a new chiral ligand for enantioselective catalysis.
Chelucci G, et al.
Tetrahedron Asymmetry, 5(3), 299-302 (1994)
Treatment of dimethyl (+)-L-tartrate with sulfur tetrafluoride.
Burmakov AI, et al.
Journal of Fluorine Chemistry, 19(2), 151-161 (1981)
Synthesis and structure of (4R, 5R)-a, a, a', a'-2, 2-hexaphenyl-4, 5-dimethanol-1, 3-dioxolane.
Irurre J, et al.
Tetrahedron Asymmetry, 3(12), 1591-1596 (1992)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service