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PHL80491

Lithospermic acid

phyproof® Reference Substance

Synonym(s):

Lithospermic acid A

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About This Item

Empirical Formula (Hill Notation):
C27H22O12
CAS Number:
Molecular Weight:
538.46
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥90.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

storage temp.

−20°C

InChI

1S/C27H22O12/c28-15-5-1-12(9-18(15)31)10-20(26(34)35)38-21(33)8-4-13-2-7-17(30)25-22(13)23(27(36)37)24(39-25)14-3-6-16(29)19(32)11-14/h1-9,11,20,23-24,28-32H,10H2,(H,34,35)(H,36,37)/b8-4+/t20-,23?,24?/m1/s1

InChI key

UJZQBMQZMKFSRV-UJVFRBSWSA-N

General description

phyproof® reference substances are valuable tools for quality control purposes of herbal raw materials, extracts, finished herbal medicinal products, dietary supplements or food products, for general scientific projects at universities or research organizations, or during screenings for new drug candidates in the pharmaceutical industry.Lithospermic acid (LSA) is isolated from the roots of Salvia mitiorrhiza, a herb used in traditional Chinese medicine. This plant-derived pharmaceutically active component is reported to exhibit various physiological effects.

Application

Lithospermic acid may be used as a reference standard for the determination of the analyte in hairy root cultures of Salvia miltiorrhiza, commercial herbal drugs, and Chinese traditional medicine by different chromatography techniques.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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The effect of lithospermic acid, an antioxidant, on development of diabetic retinopathy in spontaneously obese diabetic rats
Jin CJ, et al.
Testing, 9(6), e98232-e98232 (2014)
Determination of polyphenolic compounds in commercial herbal drugs and spices from Lamiaceae: thyme, wild thyme and sweet marjoram by chromatographic techniques
Fecka I and Turek S
Food Chemistry, 108(3), 1039-1053 (2008)
Quantitative analysis of highly similar salvianolic acids with 1H qNMR for quality control of traditional Chinese medicinal preparation Salvianolate Lyophilized Injection
Chen X, et al.
Journal of Pharmaceutical and Biomedical Analysis, 124, 281-287 (2016)
Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats
Liu X, et al.
Chemico-Biological Interactions, 176(2-3), 137-142 (2008)
Production of lithospermic acid B and rosmarinic acid in hairy root cultures of Salvia miltiorrhiza
Chen H, et al.
Journal of Industrial Microbiology & Biotechnology, 22(3), 133-138 (1999)

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