P2307
Polyvinylpyrrolidone
suitable for plant cell culture, average mol wt 10,000
Synonym(s):
PVP, Polyvidone, Povidone
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About This Item
Linear Formula:
(C6H9NO)n
CAS Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.71
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form
powder
Quality Level
mol wt
average mol wt 10,000
technique(s)
cell culture | plant: suitable
viscosity number
12-18(lit.)
SMILES string
C=CN1CCCC1=O
InChI
1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
InChI key
WHNWPMSKXPGLAX-UHFFFAOYSA-N
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Application
- Design and development of a soluble PDA-Emodin-PVP-MN patch and its anti-obesity effect in rats.: This study presents the development of a microneedle patch containing Polyvinylpyrrolidone (PVP), which enhances the delivery of anti-obesity medication, showcasing PVP′s utility in pharmaceutical formulations to improve drug solubility and efficacy (Wang H et al., 2024).
- Polyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer.: This research demonstrates the role of PVP, as a stabilizer and regulator in the synthesis of a nanodrug cocktail, indicating its critical function in nanomedicine for targeting and treating cancer effectively, thereby optimizing therapeutic outcomes (Wang C et al., 2024).
- Biochemical parameters, oxidative stress biomarkers, and anatomopathological changes in Wistar rats treated with 3′-demethoxy-6-O-demethylisoguaiacin and norisoguaiacin.: The study utilizes PVP in biomedical applications, particularly in enhancing the solubility and bioavailability of specific bioactive compounds for therapeutic purposes (Flores Jimenez NG et al., 2024).
- A water-soluble preparation for intravenous administration of isorhamnetin and its pharmacokinetics in rats.: Highlighting PVP′s importance in creating water-soluble drug formulations that facilitate the intravenous delivery of hydrophobic substances, this study explores its application in improving drug delivery systems (Rassu G et al., 2024).
- Activation of the PPAR gamma/NF-kB pathway by A-MPDA@Fe(3)O(4)@PVP via scavenging reactive oxygen species to alleviate hepatic ischemia-reperfusion injury.: This innovative study employs PVP to stabilize nanoparticle systems that actively participate in reducing oxidative stress, illustrating PVP′s potential in therapeutic interventions (Mo D et al., 2024).
Other Notes
Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The present study investigates the effect of changing spray drying temperature (40°C-120°C) and/or atomizing airflow rate (AR; 5-15 L/min) on the phase structure, physical stability, and performance of spray-dried naproxen-polyvinylpyrrolidone (PVP) K 25 amorphous solid dispersions. The modulated differential scanning
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