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Key Documents

P1061

Supelco

Proadifen hydrochloride

analytical standard, ≥95%

Synonym(s):

α-Phenyl-α-propylbenzeneacetic acid 2-(diethylamino)ethyl ester, N,N-Diethylaminoethyl 2,2-diphenylvalerate, SKF-525A

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About This Item

Empirical Formula (Hill Notation):
C23H31NO2 · HCl
CAS Number:
Molecular Weight:
389.96
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥95%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

122-123 °C

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

Cl.CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2

InChI

1S/C23H31NO2.ClH/c1-4-17-23(20-13-9-7-10-14-20,21-15-11-8-12-16-21)22(25)26-19-18-24(5-2)6-3;/h7-16H,4-6,17-19H2,1-3H3;1H

InChI key

FHIKZROVIDCMJA-UHFFFAOYSA-N

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Application

Proadifen hydrochloride may be used as an internal standard in the determination of analgesic agents like O-desmethyltramadol, tramadol and N-desmethyltramadol in human urine samples using gas chromatography coupled with mass spectrometry (GC-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase and cytochrome P450

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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David Fuchs et al.
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Simultaneous determination of tramadol, O-desmethyltramadol and N-desmethyltramadol in human urine by gas chromatography?mass spectrometry
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Journal of Chromatography. B, Biomedical Sciences and Applications, 926, 9-15 (2013)
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