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09415

Sigma-Aldrich

Sodium 4-aminosalicylate dihydrate

≥97.0% (T)

Synonym(s):

4-Amino-2-hydroxybenzoic acid sodium salt, 4-Amino-salicylic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C7H6NNaO3 · 2H2O
CAS Number:
Molecular Weight:
211.15
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥97.0% (T)

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

technique(s)

ligand binding assay: suitable

color

white to faintly beige

application(s)

peptide synthesis

SMILES string

O.O.[Na+].Nc1ccc(c(O)c1)C([O-])=O

InChI

1S/C7H7NO3.Na.2H2O/c8-4-1-2-5(7(10)11)6(9)3-4;;;/h1-3,9H,8H2,(H,10,11);;2*1H2/q;+1;;/p-1

InChI key

GMUQJDAYXZXBOT-UHFFFAOYSA-M

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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S M Vesenbeckh et al.
Infection, 40(2), 199-202 (2011-08-13)
para-Aminosalicylic acid (PAS) is commonly used in the treatment of drug-resistant tuberculosis, including multidrug-resistant tuberculosis. Since its first use in the 1940s, hypersensitivity reactions frequently limit its use in clinical practice. Cases of successful desensitization against PAS using orally administered
Shuichi Yano et al.
BMJ case reports, 2012, doi:10-doi:10 (2012-05-19)
Isoniazid (H) or rifampicin (R) mono-resistant disease can be treated easily and effectively with first-line drugs, while combined H and R resistance (ie, multidrug-resistant tuberculosis (MDRTB)) requires treatment with at least four agents, including a quinolone and an injectable agent.
[A chronic moderate manganism poisoning treated with sodium p-aminosalicylic acid].
Wei-Ping Qin et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 29(8), 619-620 (2012-02-18)
V E Sagynbaeva et al.
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (3)(3), 40-46 (2012-07-27)
Detection of IgM and IgG Chlamydia and Mycoplasma pneumoniae indicates an aggravation of intracellular infections, including, possibly, due to immunosuppressive therapy. It is possible that the intracellular infection may mediate the occurrence of certain extraintestinal manifestations of inflammatory bowel disease
Sumit Chakraborty et al.
Science (New York, N.Y.), 339(6115), 88-91 (2012-11-03)
Folate biosynthesis is an established anti-infective target, and the antifolate para-aminosalicylic acid (PAS) was one of the first anti-infectives introduced into clinical practice on the basis of target-based drug discovery. Fifty years later, PAS continues to be used to treat

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