8.52080
Fmoc-Tyr(2-ClTrt)-OH
Novabiochem®
Synonym(s):
Fmoc-Tyr(2-ClTrt)-OH, N-α-Fmoc-O-2-chlorotrityl-L-tyrosine
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About This Item
Empirical Formula (Hill Notation):
C43H34ClNO5
CAS Number:
Molecular Weight:
680.19
UNSPSC Code:
12352209
NACRES:
NA.22
Recommended Products
Quality Level
product line
Novabiochem®
Assay
≥98% (TLC)
≥99.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
hydroxyl
storage temp.
2-8°C
Related Categories
General description
The side-chain ClTrt group can be removed with 1% TFA/ 5% TIS in DCM, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support during Fmoc SPPS.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] K. Barlos, et al. (1998) J. Peptide Res., 51, 194.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] K. Barlos, et al. (1998) J. Peptide Res., 51, 194.
Linkage
Replaces: 04-12-1184
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Water (K. F.): ≤ 4.0 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Water (K. F.): ≤ 4.0 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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