An irreversible inhibitor of several cysteine proteases. Useful for alkylating cysteine and methionine residues.
Biochem/physiol Actions
Cell permeable: no
Primary Target cysteine proteases
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Toxic (F)
Reconstitution
Unstable in solution; reconstitute just prior to use.
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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The serotonin 5-HT2A receptor (5-HT2AR) is a member of the GPCR family that is important for various neurological functions and whose dysregulation causes many mental health disorders. Structural investigations of 5-HT2AR require the production of functionally active receptors expressed from
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