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P-073

Supelco

Pentazocine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C19H27NO
CAS Number:
Molecular Weight:
285.42
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

O=C(C1=C2C(NC(CCOCCC(O)=O)=O)=CC=C1)N([C@H]3CCC(NC3=O)=O)C2=O.O=C(C4=C5C(NC(CCOCCC(O)=O)=O)=CC=C4)N([C@H]6CCC(NC6=O)=O)C5=O

InChI

1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3

InChI key

VOKSWYLNZZRQPF-UHFFFAOYSA-N

Gene Information

human ... SIGMAR1(10280)

General description

A Certified Spiking Solution® applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as pain prescription monitoring, urine drug testing, forensic analysis, clinical toxicology, or pharmaceutical research. Pentazocine is a synthetic opioid analgesic used for treatment of moderate to severe pain. This painkiller is formulated in combination with naloxone or as a single agent under the trade names Talwin® and Talwin® NX, respectively.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Talwin is a registered trademark of Hospira, Inc.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Katsuhisa Kurogi et al.
Drug metabolism letters, 6(2), 109-115 (2012-09-06)
Buprenorphine, pentazocine, and naloxone are opioid drugs used for the treatment of pain and opioid dependence or overdose. Sulfation as catalyzed by the cytosolic sulfotransferases (SULTs) is involved in the metabolism of a variety of xenobiotics including drug compounds. Sulfation
Stefanie Brune et al.
Assay and drug development technologies, 10(4), 365-374 (2011-12-24)
The standard assay for the determination of σ(1) receptor affinities of novel compounds is a competitive binding assay using [(3)H]-(+)-pentazocine as radioligand and membrane preparations from guinea pig brain. Herein, a novel competitive binding assay was developed employing the hematopoietic
Robert R Luedtke et al.
Brain research, 1441, 17-26 (2012-01-31)
We previously reported that the antipsychotic drug haloperidol, a multifunctional D2-like dopamine and sigma receptor subtype antagonist, has neuroprotective properties. In this study we further examined the association between neuroprotection and receptor antagonism by evaluating a panel of novel compounds
Torahiko Terui et al.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 25(1), 53-59 (2013-01-05)
The aim of the present study was to evaluate the efficacy and safety of giving pentazocine as an analgesic with benzodiazepine during endoscopic retrograde cholangiopancreatography (ERCP). The paradoxical reactions (PR) incidence was evaluated as an indicator of usefulness. Transcutaneous arterial
Leon F Tseng et al.
Life sciences, 89(23-24), 875-877 (2011-10-13)
We have previously demonstrated that pretreatment with (+)-morphine given intrathecally attenuates the intrathecal (-)-morphine-produced tail-flick inhibition. The phenomenon has been defined as antianalgesia against (-)-morphine-produced analgesia. Present experiments were then undertaken to determine if the antianalgesic effect induced by (+)-morphine

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