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780201P

Avanti

18:1 PE MCC

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt), powder

Synonym(s):

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C53H90N2NaO11P
CAS Number:
Molecular Weight:
985.25
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 mg (780201P-100mg)
pkg of 1 × 25 mg (780201P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 780201P

shipped in

dry ice

storage temp.

−20°C

General description

18:1 PE MCC (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p- maleimidomethyl)cyclohexane-carboxamide]) lipid comprising phosphoethanolamine linked to two oleic acid by its phosphate group and to a maleimide group via its amino group. It is a maleimide-functionalized thiol-reactive lipid.

Application

18:1 PE MCC (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p- maleimidomethyl)cyclohexane-carboxamide]) has been used:
  • in proteoliposome preparation
  • in liposome preparation for tagging reporter DNA
  • in the preparation of fluorescent sulforhodamine B (SRB) dye-loaded liposomes

Packaging

5 mL Clear Glass Sealed Ampule (780201P-100mg)
5 mL Clear Glass Sealed Ampule (780201P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ja-an Annie Ho et al.
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Retromer controls epithelial cell polarity by trafficking the apical determinant Crumbs
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Current Biology, 21(13), 1111-1117 (2011)
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The evolutionarily conserved apical determinant Crumbs (Crb) is essential for maintaining apicobasal polarity and integrity of many epithelial tissues [1]. Crb levels are crucial for cell polarity and homeostasis, yet strikingly little is known about its trafficking or the mechanism

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