W269905
6-Methylcoumarin
≥99%, FCC, FG
Synonym(s):
6-methylchromen-2-one, Cocodescol, Pralina, Toncair, Toncarine
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About This Item
Empirical Formula (Hill Notation):
C10H8O2
CAS Number:
Molecular Weight:
160.17
FEMA Number:
2699
EC Number:
Council of Europe no.:
579
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
13.012
NACRES:
NA.21
Recommended Products
biological source
synthetic
Quality Level
grade
FG
Halal
Kosher
Agency
meets purity specifications of JECFA
reg. compliance
EU Regulation 1334/2008 & 178/2002
FCC
Assay
≥99%
bp
303 °C/725 mmHg (lit.)
mp
73-76 °C (lit.)
application(s)
flavors and fragrances
Documentation
see Safety & Documentation for available documents
food allergen
no known allergens
Organoleptic
coconut; creamy; sage; vanilla
SMILES string
Cc1ccc2OC(=O)C=Cc2c1
InChI
1S/C10H8O2/c1-7-2-4-9-8(6-7)3-5-10(11)12-9/h2-6H,1H3
InChI key
FXFYOPQLGGEACP-UHFFFAOYSA-N
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Application
- Development of Sustainable Insecticide Candidates for Protecting Pollinators: Insight into the Bioactivities, Selective Mechanism of Action and QSAR of Natural Coumarin Derivatives against Aphids.: This study explores the potential of 6-Methylcoumarin and other natural coumarin derivatives as sustainable insecticides, highlighting their bioactivities and selective mechanism of action. The research aims to protect pollinators while targeting aphids, providing a promising alternative to conventional pesticides (Zhou et al., 2023).
- Conductive Vial Electromembrane Extraction of Opioids from Oral Fluid.: This research presents a novel method using conductive vial electromembrane extraction for isolating opioids from oral fluid. While the primary focus is on opioids, the study utilizes 6-Methylcoumarin as a key component in the extraction process, showcasing its versatility in analytical chemistry applications (Skaalvik et al., 2023).
- 6-Methylcoumarin Promotes Melanogenesis through the PKA/CREB, MAPK, AKT/PI3K, and GSK3β/β-Catenin Signaling Pathways.: This article investigates the role of 6-Methylcoumarin in promoting melanogenesis, detailing the molecular pathways involved. The findings suggest potential applications in dermatology and cosmetic science, particularly in skin pigmentation treatments (Kim et al., 2023).
- Recursively Positive and Negative Chemotaxis Coupling with Reaction Kinetics in Self-Organized Inanimate Motion.: This research delves into the chemotactic behavior of inanimate particles, using 6-Methylcoumarin in the reaction kinetics studies. The study contributes to the understanding of self-organizing systems, with implications for material science and biophysics (Matsuo et al., 2023).
Biochem/physiol Actions
Taste at 5 ppm
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Cucurbit[8]uril (as low as 10 mol%) acts as a supramolecular catalytic nanoreaction vessel and facilitates the photodimerization of coumarins in water leading to syn dimers. Saturation kinetics shows a sigmoidal dependence with a turnover number of 3.4 min(-1) and a
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Fourier transform-infrared (4000-400 cm-1) and Raman (3500-50 cm-1) spectral measurements have been made for 6-methyl-4-bromomethylcoumarin. Equilibrium structures, harmonic vibrational frequencies, infrared intensities, and depolarization ratios have been computed at RHF/6-31G* and B3LYP/6-31G* levels of theory. Twisting CH2Br moiety in the
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Guest induced shape change of the cucurbit[8]uril cavity is likely rate limiting in the supramolecular photocatalytic cycle for CB8 mediated photodimerization of 6-methylcoumarin.
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