412554
(R)-(+)-1,2-Diaminopropane dihydrochloride
99%
Synonym(s):
(R)-(+)-Propylenediamine dihydrochloride, 1,2-Propanediamine dihydrochloride
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About This Item
Linear Formula:
CH3CH(NH2)CH2NH2·2HCl
CAS Number:
Molecular Weight:
147.05
Beilstein:
5740937
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
99%
optical activity
[α]20/D +4.0°, c = 20 in H2O
mp
241-244 °C (lit.)
functional group
amine
SMILES string
Cl[H].Cl[H].C[C@@H](N)CN
InChI
1S/C3H10N2.2ClH/c1-3(5)2-4;;/h3H,2,4-5H2,1H3;2*1H/t3-;;/m1../s1
InChI key
AEIAMRMQKCPGJR-HWYNEVGZSA-N
Related Categories
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Lorin A Thompson et al.
Bioorganic & medicinal chemistry letters, 21(22), 6909-6915 (2011-10-07)
The synthesis, evaluation, and structure-activity relationships of a set of related constrained diaminopropane inhibitors of BACE-1 are described. The full in vivo profile of an optimized inhibitor in both normal and P-gp deficient mice is compared with data generated in
Keisuke Maruyoshi et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(7), 1618-1626 (2009-01-09)
Endogenous polyamines, represented by putrescine, spermidine, and spermine, are known to exert their physiological functions by interacting with polyanionic biomolecules such as DNA, RNA, adenosine triphosphate (ATP), and phospholipids. Very few examples of conformation analysis have been reported for these
S A M Fathi et al.
Journal of hazardous materials, 164(1), 133-137 (2008-09-10)
Bis(5-bromo-2-hydroxybenzaldehyde)-1,2-propanediimine is synthesized by the reaction of 5-bromo-2-hydroxybenzaldehyde and 1,2-diaminopropane in ethanol. This ligand is used as a modifier of octadecyl silica disks for preconcentration of trace amounts of copper(II) ions, followed by nitric acid elution and flame atomic absorption
Chiral cyanide-bridged Mn(II)Mn(III) ferrimagnets, [Mn(II)(HL)(H2O)][Mn(III)(CN)6].2H2O (L = S- or R-1,2-diaminopropane): syntheses, structures, and magnetic behaviors.
Wakako Kaneko et al.
Journal of the American Chemical Society, 129(2), 248-249 (2007-01-11)
K Hamana et al.
Microbios, 103(404), 43-51 (2000-10-18)
Cellular levels of diaminopropane, putrescine and cadaverine, and decarboxylase activities to produce these diamines in six species (16 strains) of Haemophilus and four species (5 strains) of Actinobacillus belonging to the family Pasteurellaceae of the gamma subclass of the class
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