335975

(+)-1-(9-Fluorenyl)ethyl chloroformate solution

18 mM in acetone, for chiral derivatization

• Synonym(s): (+)-FLEC solution
• Empirical Formula (Hill Notation): C₁₆H₁₃ClO₂
• CAS Number: 107474-79-3
• Molecular Weight: 272.73
• MDL number: MFCD00043429
• UNSPSC Code: 12352005
• PubChem Substance ID: 24860354
• NACRES: NA.22

Properties

• grade: for chiral derivatization
• vapor density: 2 (vs air)
• vapor pressure: 180 mmHg ( 20 °C)
• form: liquid
• concentration: 18 mM in acetone
• refractive index: n20/D 1.3602
• density: 0.79 g/mL at 25 °C
• storage temp.: 2-8°C
• InChI: 1S/C16H13ClO2/c1-10(19-16(17)18)15-13-8-4-2-6-11(13)12-7-3-5-9-14(12)15/h2-10,15H,1H3
• InChI key: SFRVOKMRHPQYGE-UHFFFAOYSA-N

Description

General description

(+)-1-(9-Fluorenyl)ethyl chloroformate is a highly fluorescent compound1 commonly used as a chiral derivatizing agent for the separation of racemates prior to reversed-phase HPLC analysis.

Application

• Chiral analysis of β-methylamino alanine (BMAA) enantiomers: Details the use of (+)-1-(9-fluorenyl)-ethyl chloroformate (FLEC) for derivatization followed by LC-MS/MS analysis, improving the understanding of amino acids′ stereochemistry (Zurita et al., 2019).
• Enantioselective micellar electrokinetic chromatography of dl‐amino acids: Utilizes (+)-1-(9-fluorenyl)ethyl chloroformate derivatization combined with UV-induced fluorescence detection to analyze amino acids, enhancing analytical methodologies (Prior et al., 2018).

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H318,H336
• Precautionary Statements: P210 - P280 - P304 + P340 + P312 - P305 + P351 + P338 + P310 - P403 + P235
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system
• Supplementary Hazards: EUH066
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 1.4 °F
• Flash Point(C): -17 °C