177466
4-Methylcyclohexylamine, mixture of cis and trans
97%
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About This Item
Recommended Products
Quality Level
Assay
97%
form
liquid
refractive index
n20/D 1.4531 (lit.)
bp
151-154 °C (lit.)
density
0.855 g/mL at 25 °C (lit.)
SMILES string
CC1CCC(N)CC1
InChI
1S/C7H15N/c1-6-2-4-7(8)5-3-6/h6-7H,2-5,8H2,1H3
InChI key
KSMVBYPXNKCPAJ-UHFFFAOYSA-N
General description
Trans-4-methylcyclohexylamine is a spermidine synthase inhibitor.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 3 - Skin Corr. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
80.6 °F - closed cup
Flash Point(C)
27 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Biological & pharmaceutical bulletin, 28(4), 569-573 (2005-04-02)
In rat tissues, a decrease in spermidine, accompanied by an increase in spermine was induced by the oral administration (once daily for either 1 week or 1 month) of trans-4-methylcyclohexylamine (4MCHA), a spermidine synthase inhibitor. This is similar to the
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A close relationship between rat liver regeneration and the concentration ratio of spermidine to spermine (spd:spm) was demonstrated by the oral administration of trans-4-methylcyclohexylamine (MCHA), a specific inhibitor of putrescine aminopropyltransferase. A decrease in recovery rate of remnant liver with
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