Skip to Content
Merck
All Photos(1)

Key Documents

102245

Sigma-Aldrich

2-(Dimethylamino)pyridine

97%

Synonym(s):

2,6-Dimethyl-3-pyridinylamine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C7H10N2
CAS Number:
Molecular Weight:
122.17
Beilstein:
110353
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

refractive index

n20/D 1.559 (lit.)

bp

191 °C (lit.)

density

0.984 g/mL at 25 °C (lit.)

SMILES string

CN(C)c1ccccn1

InChI

1S/C7H10N2/c1-9(2)7-5-3-4-6-8-7/h3-6H,1-2H3

InChI key

PSHKMPUSSFXUIA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

2-(Dimethylamino)pyridine is a clear, colorless to light yellow liquid.

Application

2-(Dimethylamino)pyridine in toluene at room temperature in the presence of 1.1 equivalent of methyl trifluoromethanesulfonate forms (2-pyridyl)-trimethylammonium trifluoromethanesulfonate salt. It is used as a model substrate in the preparation of chelate carbene via cyclometalation, H2 loss and reversible α-elimination.

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

2-, 3-and 4-[18F] Fluoropyridine by no-carrier-added nucleophilic aromatic substitution with K [18F] F-K222-a comparative study.
Karramkam M, et al.
Journal of Labelled Compounds & Radiopharmaceuticals, 46(10), 979-992 (2003)
Farideh Mahmoodzadeh et al.
International journal of biological macromolecules, 126, 517-524 (2018-12-30)
Conventional chemotherapy suffers lack of bioavailability, selectivity and multidrug resistance (MDR). Nano-sized drug delivery systems (DDS) is developing aimed to solve several limitations of conventional drug delivery systems. These systems have been offered for targeting tumor tissue due to their
Sagarika Samantray et al.
Nature communications, 11(1), 880-880 (2020-02-16)
A self-assembled coordination cage usually possesses one well-defined three-dimensional (3D) cavity whereas infinite number of 3D-cavities are crafted in a designer metal-organic framework. Construction of a discrete coordination cage possessing multiple number of 3D-cavities is a challenging task. Here we
Yingqi Xu et al.
International journal of pharmaceutics, 522(1-2), 21-33 (2017-02-22)
Mitochondria are important targets for the intracellular delivery of drugs and DNA. For mitochondria-targeted delivery, a mitochondriotropic molecule, triphenylphosphonium (TPP), was applied to the synthesis of amphiphilic TPP-poly(ethylene glycol)-poly(ε-caprolactone) (TPP-PEG-PCL) polymers. The TPP-PEG-PCL polymer was used to prepare micelles using
Eric Clot et al.
Journal of the American Chemical Society, 126(28), 8795-8804 (2004-07-15)
[H2Ir(OCMe2)2L2]BF4 (1) (L = PPh3), a preferred catalyst for tritiation of pharmaceuticals, reacts with model substrate 2-(dimethylamino)pyridine (py-NMe2; py = 2-pyridyl) to give chelate carbene [H2Ir(py-N(Me)CH=)L2]BF4 (2a) via cyclometalation, H2 loss, and reversible alpha-elimination. Agostic intermediate [H2Ir(py-N(Me)CH2-H)L2]BF4) (4a), seen by

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service