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Photochemical behavior of biosupramolecular assemblies of photosensitizers, cucurbit[n]urils and albumins.

Physical chemistry chemical physics : PCCP (2017-01-07)
Javiera Cáceres, José Robinson-Duggon, Anita Tapia, Constanza Paiva, Matías Gómez, Cornelia Bohne, Denis Fuentealba
RÉSUMÉ

Biosupramolecular assemblies combining cucurbit[n]urils (CB[n]s) and proteins for the targeted delivery of drugs have the potential to improve the photoactivity of photosensitizers used in the photodynamic therapy of cancer. Understanding the complexity of these systems and how it affects the properties of photosensitizers is the focus of this work. We used acridine orange (AO

MATÉRIAUX
Référence du produit
Marque
Description du produit

Sigma-Aldrich
Bis(cyclopentadienyl)cobalt(III) hexafluorophosphate, 98%
Sigma-Aldrich
Acridine Orange hydrochloride solution, 10 mg/mL in H2O, ≥95.0% (HPLC)