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In vivo biodistribution of antihyperglycemic biopolymer-based nanoparticles for the treatment of type 1 and type 2 diabetes.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V (2016-12-23)
Marlene Lopes, Denise Aniceto, Margarida Abrantes, Susana Simões, Fábio Branco, Isabel Vitória, M Filomena Botelho, Raquel Seiça, Francisco Veiga, António Ribeiro
RÉSUMÉ

This study aimed to assess the biodistribution of antihyperglycemic insulin-loaded alginate/dextran sulfate-based nanoparticles dual coated with chitosan and technetium-99m-albumin (

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Sigma-Aldrich
Succinic dihydrazide, 96%