- Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing.
Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing.
Science advances (2021-10-21)
Andry Andrianarivelo, Estefani Saint-Jour, Paula Pousinha, Sebastian P Fernandez, Anna Petitbon, Veronique De Smedt-Peyrusse, Nicolas Heck, Vanesa Ortiz, Marie-Charlotte Allichon, Vincent Kappès, Sandrine Betuing, Roman Walle, Ying Zhu, Charlène Joséphine, Alexis-Pierre Bemelmans, Gustavo Turecki, Naguib Mechawar, Jonathan A Javitch, Jocelyne Caboche, Pierre Trifilieff, Jacques Barik, Peter Vanhoutte
PMID34669474
RÉSUMÉ
[Figure: see text].
MATÉRIAUX
Référence du produit
Marque
Description du produit
Sigma-Aldrich
Anti-D1 Dopamine Receptor antibody,Rat monoclonal, clone 1-1-F11 s.E6, purified from hybridoma cell culture
Sigma-Aldrich
Anticorps anti-récepteur dopaminergique D2, from rabbit, purified by affinity chromatography