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1317007

USP

Hydrocortisone 21-acetate

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

21-acétate de 11β,17α,21-trihydroxy-4-pregnène-3,20-dione, 21-acétate de 17-hydroxycorticostérone, 21-acétate de 4-pregnène-11β,17α,21-triol-3,20-dione, Acétate de 17-α-hydroxycorticostérone

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About This Item

Formule empirique (notation de Hill):
C23H32O6
Numéro CAS:
50-03-3
Poids moléculaire :
404.50
Numéro Beilstein :
2066841
Numéro MDL:
MFCD00037714
Code UNSPSC :
41116107
ID de substance PubChem :
329750076
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

hydrocortisone

Fabricant/nom de marque

USP

Pf

223 °C (dec.) (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O

InChI

1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1

Clé InChI

ALEXXDVDDISNDU-JZYPGELDSA-N

Informations sur le gène

human ... NR3C1(2908)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydrocortisone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Hydrocortisone Acetate Cream
  • Hydrocortisone Acetate Lotion
  • Hydrocortisone Acetate Ointment
  • Neomycin Sulfate and Hydrocortisone Acetate Ointment
  • Neomycin Sulfate and Hydrocortisone Acetate Ophthalmic Suspension
  • Oxytetracycline Hydrochloride and Hydrocortisone Acetate Ophthalmic Suspension
  • Neomycin and Polymyxin B Sulfates and Hydrocortisone Acetate Cream

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1014

Hydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material

1316004

Hydrocortisone, United States Pharmacopeia (USP) Reference Standard

1317302

Hydrocortisone butyrate, United States Pharmacopeia (USP) Reference Standard

1319002

Hydrocortisone hemisuccinate, United States Pharmacopeia (USP) Reference Standard

H1400000

Hydrocortisone 21-acetate, European Pharmacopoeia (EP) Reference Standard

H1300000

Hydrocortisone, European Pharmacopoeia (EP) Reference Standard

H1425000

Hydrocortisone hydrogen succinate, European Pharmacopoeia (EP) Reference Standard

Y0001092

Hydrocortisone, European Pharmacopoeia (EP) Reference Standard

Y0001482

Hydrocortisone 21-acetate, European Pharmacopoeia (EP) Reference Standard

1321004

Hydrocortisone valerate, United States Pharmacopeia (USP) Reference Standard

1320001

Hydrocortisone phosphate triethylamine, United States Pharmacopeia (USP) Reference Standard

BP576

Hydrocortisone, British Pharmacopoeia (BP) Assay Standard

BP584

Hydrocortisone 21-acetate, British Pharmacopoeia (BP) Reference Standard

BP187

Hydrocortisone hydrogen succinate, British Pharmacopoeia (BP) Reference Standard

PHR1926

Hydrocortisone Hemisuccinate, Pharmaceutical Secondary Standard; Certified Reference Material

BP188

Hydrocortisone sodium phosphate, British Pharmacopoeia (BP) Reference Standard

PHR2160

Hydrocortisone Impurity J, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2157

Hydrocortisone Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2162

Hydrocortisone Impurity L, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2161

Hydrocortisone Impurity K, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2159

Hydrocortisone Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2163

Hydrocortisone Impurity M, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2158

Hydrocortisone Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2164

6a-Hydroxyhydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2156

Hydrocortisone Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3185

Hydrocortisone Valerate, pharmaceutical secondary standard, certified reference material

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H360Df,H373

Classification des risques

Repr. 1B - STOT RE 2

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Adamo Fini et al.
AAPS PharmSciTech, 9(3), 762-768 (2008-06-20)
The purpose of this research was the preparation of four formulations containing hydrocortisone acetate (HCA) for topical application, including two aqueous systems (hydrophilic microemulsion and aqueous gel) and two systems with dominant hydrophobicity (hydrophobic microemulsion and ointment). The formulations were
Timothy Kassis et al.
PLoS neglected tropical diseases, 8(11), e3305-e3305 (2014-11-21)
Lymphatic Filariasis, a Neglected Tropical Disease, is caused by thread-like parasitic worms, including B. malayi, which migrate to the human lymphatic system following transmission. The parasites reside in collecting lymphatic vessels and lymph nodes for years, often resulting in lymphedema
Janyce A Sugui et al.
Journal of clinical microbiology, 52(10), 3707-3721 (2014-08-08)
Aspergillus section Fumigati contains 12 clinically relevant species. Among these Aspergillus species, A. fumigatus is the most frequent agent of invasive aspergillosis, followed by A. lentulus and A. viridinutans. Genealogical concordance and mating experiments were performed to examine the relationship
Dan-Ni Wang et al.
Medical mycology, 52(5), 506-518 (2014-05-23)
Gliotoxin is an important virulence factor of Aspergillus fumigatus. Although GliA putatively belongs to the major facilitator superfamily in the gliotoxin biosynthesis cluster, its roles remain unclear. To determine the function of GliA, we disrupted gliA in A. fumigatus. gliA

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