1285873

Fluticasone propionate

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester
• Formule empirique (notation de Hill): C₂₅H₃₁F₃O₅S
• Numéro CAS: 80474-14-2
• Poids moléculaire : 500.57
• Numéro MDL: MFCD00866007
• Code UNSPSC : 41116107
• ID de substance PubChem : 329749903
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: fluticasone
• Fabricant/nom de marque: USP
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
• InChI: 1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
• Clé InChI: WMWTYOKRWGGJOA-CENSZEJFSA-N
• Informations sur le gène: human ... NR3C1(2908)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fluticasone propionate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Fluticasone Propionate and Salmeterol Inhalation Aerosol^®
• Fluticasone Propionate and Salmeterol Inhalation Powder
• Fluticasone Propionate Cream
• Fluticasone Propionate Inhalation Aerosol^®
• Fluticasone Propionate Inhalation Powder
• Fluticasone Propionate Lotion

Actions biochimiques/physiologiques

Fluticasone propionate is a second generation glucocorticoid. Used as an anti-inflammatory agent for asthma. Shown to enhance eosinophil apoptosis in a concentration-dependent manner via the glucocorticoid receptor.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations légales

Aerosol is a registered trademark of Cytec Technology Corp.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H361f,H373
• Conseils de prudence: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Repr. 2 - STOT RE 2
• Organes cibles: Endocrine system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable