1176506

Dexamethasone 21-acetate

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : Dexamethasone 21-acetate, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
• Formule empirique (notation de Hill): C₂₄H₃₁FO₆
• Numéro CAS: 1177-87-3
• Poids moléculaire : 434.50
• Numéro Beilstein : 2342608
• Numéro MDL: MFCD00027407
• Code UNSPSC : 41116107
• ID de substance PubChem : 329749549
• Nomenclature NACRES : NA.24

Propriétés

• Source biologique: synthetic
• Qualité: pharmaceutical primary standard
• Agence: USP
• Pression de vapeur: <0.0000001 kPa ( 25 °C)
• Famille d'API: dexamethasone
• Forme: powder
• Conditionnement: pkg of 200 mg
• Fabricant/nom de marque: USP
• Couleur: white
• Pf: 460.4-464 °F (238—240°C)
• Solubilité: acetone: freely soluble; dichloromethane: slightly soluble; methanol: freely soluble; water: practically insoluble
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
• Clé InChI: AKUJBENLRBOFTD-RPRRAYFGSA-N
• Informations sur le gène: human ... NR3C1(2908)

Description

Description générale

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids, commonly used as a pharmaceutical ingredient in creams, ointments, microemulsions, lotions, aerosols, etc.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Betamethasone Acetate
• Ciprofloxacin and Dexamethasone Otic Suspension
• Dexamethasone
• Dexamethasone Acetate
• Dexamethasone Acetate Injectable Suspension

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H360FD
• Conseils de prudence: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Repr. 1B
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable