53353-U
Ascentis® Express 90 Å Phenyl-Hexyl (2.7 μm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
Synonyme(s) :
Core-shell (SPP) Fused Core Phenyl HPLC column
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About This Item
Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52
Produits recommandés
product name
Ascentis® Express Phenyl-Hexyl, 2.7 μm HPLC Column, 2.7 μm particle size, L × I.D. 15 cm × 4.6 mm
Matériaux
stainless steel column
Niveau de qualité
Agence
suitable for USP L11
Gamme de produits
Ascentis®
Caractéristiques
endcapped
Fabricant/nom de marque
Ascentis®
Conditionnement
1 ea of
Paramètres
60 °C temp. range
600 bar max. pressure (9000 psi)
Technique(s)
HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable
L × D.I.
15 cm × 4.6 mm
Superficie
135 m2/g
Impuretés
<5 ppm metals
Matrice
Fused-Core particle platform
superficially porous particle
Groupe de la matrice active
phenylhexyl phase
Taille des particules
2.7 μm
Dimension de pores
90 Å
Plage de pH
2-9
Application(s)
food and beverages
Technique de séparation
reversed phase
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Description générale
The Phenyl-Hexyl phase has unique selectivity arising from solute interaction with the aromatic ring and its delocalized electrons. It is complementary (orthogonal) to both C18 and RP-Amide phases because of this unique aromaticity. The Phenyl-Hexyl phase also tend to exhibit good shape selectivity, which may originate from solute multipoint interaction with the planar ring system. More retention and selectivity will often be observed for solutes with aromatic electron-withdrawing groups (fluorine, nitro, etc.) or with a delocalized heterocyclic ring system such as the benzodiazepine compounds.
Application
- A Different Perspective on the Characterization of a New Degradation Product of Flibanserin With HPLC-DAD-ESI-IT-TOF-MSn and Its Pharmaceutical Formulation Analysis With Inter-Laboratory Comparison.: This study utilizes the Ascentis® Express Phenyl-Hexyl, 2.7 μm HPLC column to characterize degradation products of flibanserin, demonstrating its efficacy in high-resolution analytical applications (Geven et al., 2023).
- HPLC with spectrophotometric or mass spectrometric detection for quantifying very-long chain fatty acids in human plasma and its association with cardiac risk factors.: The Ascentis® Express Phenyl-Hexyl column was employed for precise quantification of fatty acids, linking its use to critical clinical research on cardiac risk factors (Shrestha et al., 2021).
- A fully automated and fast method using direct sample injection combined with fused-core column on-line SPE-HPLC for determination of ochratoxin A and citrinin in lager beers.: This research highlights the efficiency of the Ascentis® Express Phenyl-Hexyl column in detecting contaminants in beverages, emphasizing its role in food safety analysis (Lhotska et al., 2016).
- A study of retention characteristics and quality control of nutraceuticals containing resveratrol and polydatin using fused-core column chromatography.: This study explores the retention characteristics of nutraceuticals using the Ascentis® Express Phenyl-Hexyl column, showcasing its utility in quality control of health supplements (Fibigr et al., 2016).
- An on-line SPE-HPLC method for effective sample preconcentration and determination of fenoxycarb and cis, trans-permethrin in surface waters.: The Ascentis® Express Phenyl-Hexyl column was integral in preconcentrating and analyzing pesticide residues in environmental samples, underscoring its environmental analytical applications (Satinsky et al., 2015).
Informations légales
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Colonne de garde
Réf. du produit
Description
Tarif
Nécessaire, mais non fourni
Réf. du produit
Description
Tarif
Produit(s) apparenté(s)
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Certificats d'analyse (COA)
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Les clients ont également consulté
C M Chavez-Eng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1011, 204-214 (2016-01-17)
An ultra-high performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method for the simultaneous determination of (4S,5R)-5-[3,5-bis (trifluoromethyl)phenyl]-3-{[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl] methyl}-4-methyl-1,3-oxazolidin-2-one (anacetrapib, I) and [(13)C5(15)N]-anacetrapib, II in human plasma has been developed to support a clinical study to determine the absolute bioavailability of I.
E Lesellier
Journal of chromatography. A, 1266, 34-42 (2012-11-03)
The recent introduction of new stationary phases for liquid chromatography based on superficially porous particles, called core-shell or fused-core, dramatically improved the separation performances through very high efficiency, due mainly to reduced eddy diffusion. However, few studies have evaluated the
Petr Chocholouš et al.
Talanta, 103, 221-227 (2012-12-04)
Currently, for Sequential Injection Chromatography (SIC), only reversed phase C18 columns have been used for chromatographic separations. This article presents the first use of three different stationary phases: three core-shell particle-packed reversed phase columns in flow systems. The aim of
Ivona Lhotská et al.
Analytical and bioanalytical chemistry, 408(12), 3319-3329 (2016-03-20)
A new fast and sensitive method based on on-line solid-phase extraction on a fused-core precolumn coupled to liquid chromatography with fluorescence detection has been developed for ochratoxin A (OTA) and citrinin (CIT) determination in lager beer samples. Direct injection of
Alex D Batista et al.
Talanta, 133, 142-149 (2014-12-02)
On-line sample pretreatment (clean-up and analyte preconcentration) is for the first time coupled to sequential injection chromatography. The approach combines anion-exchange solid-phase extraction and the highly effective pentafluorophenylpropyl (F5) fused-core particle column for separation of eight sulfonamide antibiotics with similar
Articles
Improve your reversed phase selectivity for polar aromatics and heterocyclic compounds with the Ascentis® Express Phenyl-Hexyl U/HPLC column.
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