U2625

Uric acid

≥99%, crystalline

• Synonyme(s) : 2,6,8-Trihydroxypurine
• Formule empirique (notation de Hill): C₅H₄N₄O₃
• Numéro CAS: 69-93-2
• Poids moléculaire : 168.11
• Numéro Beilstein : 156158
• Numéro CE : 200-720-7
• Numéro MDL: MFCD00005712
• Code UNSPSC : 12352005
• ID de substance PubChem : 24900634
• Nomenclature NACRES : NA.55

Propriétés

• Niveau de qualité: 100; 200
• Pureté: ≥99%
• Forme: crystalline
• Pf: >300 °C (lit.)
• Chaîne SMILES: O=C1NC(=O)C2=C(N1)NC(=O)N2
• InChI: 1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
• Clé InChI: LEHOTFFKMJEONL-UHFFFAOYSA-N

Description

Application

Uric acid has been used:

• in inducing hyperuricemia in mice
• as a component of digestion fluid for the simulation of in vitro human digestion model
• in selectivity test of the glucose sensor in sweat-based diabetes monitoring

Actions biochimiques/physiologiques

Uric acid is an insoluble catabolite produced by adenine and guanine metabolism. Accumulation of uric acid leads to gout, hyperuricemia, arthritis and renal failure. Elevated uric acid levels contributes to hypertension and pathogenesis of cardiovascular disease. Low uric acid levels associated with Parkinson′s disease and multiple sclerosis, may elicit protective functionality. High levels of uric acid in patients with chronic obstructive pulmonary disease (COPD) may serve as potential marker for diagnosis.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)