T1875

Testosterone propionate

solid

• Synonyme(s) : 17β-hydroxy-4-androstène-3-one 17-propionate, 4-androstène même-17β-ol-3-one 17-propionate
• Formule empirique (notation de Hill): C₂₂H₃₂O₃
• Numéro CAS: 57-85-2
• Poids moléculaire : 344.49
• Numéro Beilstein : 3221760
• Numéro CE : 200-351-1
• Numéro MDL: MFCD00003653
• Code UNSPSC : 51111800
• ID de substance PubChem : 24899994
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Stérilité: non-sterile
• Pureté: ≥98% (HPLC)
• Forme: solid
• Contrôle du médicament: USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• Couleur: white
• Solubilité: acetone: soluble 1 in 4 of acetone; chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow; ethanol: soluble 1 in 6 of ethanol; ethyl oleate: soluble 1 in 20 of ethyl oleate; propylene glycol: soluble 1 in 30 of propylene glycol; soluble 1 in 20 of ethyl oleate; ethanol: 10 mg/mL; 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.4 mg/mL; H₂O: insoluble; oil: soluble
• Conditions d'expédition: ambient
• Température de stockage: room temp
• Chaîne SMILES: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(=O)CC
• InChI: 1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1
• Clé InChI: PDMMFKSKQVNJMI-BLQWBTBKSA-N
• Informations sur le gène: human ... AR(367) , CYP17A1(1586) ; rat ... Ar(24208)

Description

Application

Testosterone propionate has been used for studying its effects on pregnant ewes,.

Actions biochimiques/physiologiques

Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it regulates several biological functions. Testosterone propionate has been synthetically derived from a plant. This product has extended and faster-acting functions when compared to other testosterone esters.

Forme physique

Photosensitive solid

Notes préparatoires

This product is soluble in chloroform (50 mg/ml). It is also soluble in various oils. The oil solutions can be sterilized by maintaining at 150 deg C for 1 hour. It is practically insoluble in water, soluble 1 in 6 of ethanol, 1 in 4 of acetone, 1 in 20 of ethyl oleate, and 1 in 30 of propylene glycol. The product is incompatible with alkalis and oxidizing agents and it should be protected from light.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H302,H351,H360FD,H400
• Conseils de prudence: P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313
• Classification des risques: Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1A
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges