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T1539

Sigma-Aldrich

(+)-α-Tocopherol

Type VI, from vegetable oil, liquid (≥0.88M based on potency, density and molecular wt.), BioReagent, suitable for insect cell culture, ≥1000 IU/g

Synonyme(s) :

2,5,7,8-Tetramethyl-2-(4′,8′,12′-trimethyltridecyl)-6-chromanol, 5,7,8-Trimethyltocol, D-α-Tocopherol, Vitamin E

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About This Item

Formule empirique (notation de Hill):
C29H50O2
Numéro CAS:
59-02-9
Poids moléculaire :
430.71
Numéro Beilstein :
4712525
Numéro CE :
200-412-2
Numéro MDL:
MFCD00072045
Code UNSPSC :
12352205
eCl@ss :
34058016
ID de substance PubChem :
24899979
Nomenclature NACRES :
NA.75

Source biologique

vegetable oil

Niveau de qualité

200

Type

Type VI

Gamme de produits

BioReagent

Forme

liquid (≥0.88M based on potency, density and molecular wt.)

Puissance

≥600 mg d-α-tocopherol per g

Activité spécifique

≥1000 IU/g

Poids mol.

Mw 430.71 g/mol

Concentration

≥600 mg/g

Technique(s)

cell culture | insect: suitable

Couleur

yellow-orange

Indice de réfraction

n20/D 1.505 (lit.)

Point d'ébullition

200-220 °C/0.1 mmHg (lit.)

Solubilité

chloroform: soluble 0.1 mL/mL, clear, faintly yellow to yellow

Densité

0.95 g/mL at 25 °C (lit.)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1

Clé InChI

GVJHHUAWPYXKBD-IEOSBIPESA-N

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Application

Use in insect cell culture applications as an antioxidant.

Autres remarques

Mixed constitutional (α, β, γ, δ) isomers.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

230.0 °F - closed cup

Point d'éclair (°C)

110 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

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Ying Yang et al.
Food chemistry, 141(1), 473-481 (2013-06-19)
Vitamin E is an essential micronutrient for humans and animals due to its antioxidant and non-antioxidant biological activities. The α-tocopherol acetate form is often used in foods and other products due to its high biological activity and chemical stability. In
Jen-Hao Cheng et al.
European journal of medicinal chemistry, 46(4), 1222-1231 (2011-02-25)
In an effort to develop novel antioxidant as anticancer agents, a series of xanthones were prepared. In vitro screening, the synthetic xanthones revealed significant inhibitory effects on xanthine oxidase and ABTS radical-cation scavenging activity. The selective compounds 2 and 8
Karl Michaëlsson et al.
The American journal of clinical nutrition, 99(1), 107-114 (2013-11-15)
A reduction in the formation of free radicals and oxidative stress might reduce the rate of bone loss and muscle wasting. The objective was to determine whether α-tocopherol intake or serum concentrations are associated with fracture risk in older women
Y Loetscher et al.
Poultry science, 92(11), 2938-2948 (2013-10-19)
Prevention of lipid oxidation needs special attention because a high proportion of fatty acids in broiler meat are unsaturated. A feeding experiment was conducted to evaluate the antioxidant effect of dietary addition of rosemary, chokeberry pomace, rosehip, or nettle in
Laura L Baxter et al.
Nutrients, 4(6), 467-490 (2012-07-24)
Vitamin E isoforms are essential nutrients that are widely used as dietary supplements and therapeutic agents for a variety of diseases. However, their pharmacokinetic (PK) properties remain poorly characterized, and high dosage animal studies may provide further information on their
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Vitamin E, Tocopherol, in Cell Culture

Importance and uses of vitamin E (tocopherol) in serum-free eukaryotic, including hybridoma and chinese hamster ovary (CHO), cell cultures.

Vitamin E, Tocopherol, in Cell Culture

Importance and uses of vitamin E (tocopherol) in serum-free eukaryotic, including hybridoma and chinese hamster ovary (CHO), cell cultures.

Vitamin E, Tocopherol, in Cell Culture

Importance and uses of vitamin E (tocopherol) in serum-free eukaryotic, including hybridoma and chinese hamster ovary (CHO), cell cultures.

Vitamin E, Tocopherol, in Cell Culture

Importance and uses of vitamin E (tocopherol) in serum-free eukaryotic, including hybridoma and chinese hamster ovary (CHO), cell cultures.

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