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Key Documents

T0195

Sigma-Aldrich

α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus (Formosan Banded Krait)

Synonyme(s) :

TMR-α-BTX

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About This Item

Numéro MDL:
Code UNSPSC :
12352116
Nomenclature NACRES :
NA.77

Poids mol.

~8,500

Niveau de qualité

Couleur

red

Solubilité

H2O: soluble

Température de stockage

−20°C

Application

α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus was used at a dilution of 1:220 to identify the distribution of nicotinic acetylcholine receptors at neuromuscular junctions of longitudinal sections of rat gastrocnemius muscle.
α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus (Formosan Banded Krait) has been used in immunofluorescence staining (1:200) for identification of neuromuscular junction in experimental models. It has also been used to block muscle contraction in myotome cells.

Actions biochimiques/physiologiques

α-Bungarotoxin is a high-affinity antagonist for nicotinic acetylcholine receptors (AChRs) from muscle but not the neurons. Labeling α-Bungarotoxin with tetramethylrhodamine enables the detection of bungarotoxin-binding receptors at neuromuscular junctions.
Useful for detecting the distribution of nicotinic acetylcholine receptors at neuromuscular junctions.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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