SRP6058

Kallikrein-3 human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

• Synonyme(s) : APS, Hk3, KLK2A1, Kallikrein-3, P-30 antigen, PSA
• Numéro CAS: 1362692-52-1
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: human
• Produit recombinant: expressed in human cells
• Pureté: ≥95% (SDS-PAGE)
• Forme: lyophilized
• Poids mol.: 35 kDa
• Conditionnement: pkg of 20 μg
• Numéro d'accès NCBI: P07288
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: human ... KLK3(354)

Description

Description générale

Prostate-specific antigen, also known as Gamma-seminoprotein, Kallikrein-3, kallikrein-related peptidase 3, Semenogelase, KLK3 and PSA, is a secreted protein which belongs to thepeptidase S1 family and Kallikrein subfamily. KLK3/Kallikrein 3 contains one peptidase S1 domain. KLK3/Kallikrein 3 is a glycoprotein produced almost exclusively by the prostate gland. KLK3/Kallikrein 3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely.It is also believed to be instrumental in dissolving the cervical mucous, allowing the entry of sperm. Human KLK3/Kallikrein 3 and human KLK2 are closely related products of the human kallikrein genes KLK3 and KLK2, respectively. Both KLK3/Kallikrein 3 and human kallikrein 2 are produced and secreted in the prostate and have important applications in the diagnosis of prostate cancer. Understanding the mechanism by which genetic variation in KLK3/Kallikrein 3 affects prostate cancer risk has important implications for study of the biological role of KLK3/Kallikrein 3 in prostate tumorigenesis.

Forme physique

Lyophilized from sterile PBS, pH 7.4. (Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.)

Notes préparatoires

Centrifuge the vial prior to opening.

Reconstitution

Detailed reconstitution instructions are sent along with the product.

Clause de non-responsabilité

Ce produit, destiné à la recherche scientifique, est soumis à une réglementation spécifique en France, y compris pour les activités d′importation et d′exportation (Article L 1211-1 alinéa 2 du Code de la Santé Publique). L′acheteur (c′est-à-dire l′utilisateur FINAL) est tenu d′obtenir une autorisation d′importation auprès du ministère français de la recherche, mentionné à l′article L1245-5-1 II du Code de la Santé Publique. En commandant ce produit, vous confirmez détenir l′autorisation d′importation requise.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable