SCP0195
MOG Protein 35-55, MOG Peptide Fragment human
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About This Item
Formule empirique (notation de Hill):
C120H179N35O28S1
Poids moléculaire :
2591.99
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.32
Produits recommandés
Pureté
≥95% (HPLC)
Forme
lyophilized
Composition
Peptide Content, ≥75%
Conditions de stockage
protect from light
Température de stockage
−20°C
Amino Acid Sequence
Met-Glu-Val-Gly-Trp-Tyr-Arg-Pro-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys
Description générale
Myelin oligodendrocyte glycoprotein (MOG) is widely expressed at the extracellular surface of myelin sheaths and oligodendrocytes in the central nervous system. The MOG gene is mapped to human chromosome 6p22.1.
Application
MOG Protein 35-55 is used as an antigen/immunogen to induce anti-MOG antibodies to induce experimental diseases such as experimental autoimmune encephalomyelitis (EAE) for study.
Actions biochimiques/physiologiques
Myelin oligodendrocyte glycoprotein (MOG) is believed to function as an adhesion protein that support myelination of nerves. MOG is studied to understand the mechanisms of diseases such as adrenoleukodystrophy, vanishing white matter disease, multiple sclerosis (MS) and Rubella-induced mental retardation.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Huifen Huang et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 29(5), 535-545 (2020-05-28)
Multiple sclerosis (MS) is an autoimmune disease characterized by a loss of myelin, limb disabilities and dysregulation of gene expression. Unfortunately, there still is no treatment to cure MS. To explore a novel way to treat MS using currently available
Antibodies to myelin oligodendrocyte glycoprotein in idiopathic optic neuritis.
Nakajima H, et al.
BMJ Open, 5(4), e007766-e007766 (2015)
Immune modulation by a tolerogenic myelin oligodendrocyte glycoprotein (MOG) 10?60 containing fusion protein in the marmoset experimental autoimmune encephalomyelitis model.
Kap YS, et al.
Clinical and Experimental Immunology, 180(1), 28-39 (2015)
The discoidin domain receptor 1 as a novel susceptibility gene for schizophrenia.
Roig B, et al.
Molecular Psychiatry, 12(9), 833-833 (2007)
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