SAB5600004

Anti-Mouse IgG2c antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM223, purified immunoglobulin

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.46

Propriétés

• Produit recombinant: expressed in HEK 293 cells
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: RM223, monoclonal; recombinant monoclonal
• Forme: buffered aqueous glycerol solution
• Espèces réactives: mouse
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 0.01 μg/mL; immunoblotting: 0.5-2 μg/mL (non-reduced only); immunocytochemistry: 0.5-2 μg/mL; immunohistochemistry: 0.5-2 μg/mL
• Isotype: IgG
• Numéro d'accès NCBI: 404711
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified

Description

Description générale

IgG2c codes for Igh-1b. In mice, IgG2a and IgG2c are arranged in tandem on identical chromosome as two visible loci.

Spécificité

This antibody reacts to the Fc region of mouse IgG2c. No cross reactivity with mouse IgG1, IgG2a, IgG2b, IgG3, IgM, IgA, IgE, human IgG, or rat IgG.

Immunogène

Purified mouse IgG2c whole molecule

Actions biochimiques/physiologiques

Mouse IgG2c generate several unique non-bonded interactions between the BC, DE and FG loops than mIgG2b. It connects to FcγRIV (Fc γ receptor IV) with a high affinity in the complex-type glycoform. In mice, IgG2c has unique immune profiles like, response, immune-decoration, because of their difference in protein sequence.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable