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Key Documents

SAB5500058

Sigma-Aldrich

Anti-CD3 antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP7, tissue culture supernatant

Synonyme(s) :

Anti-CD3epsilon, Anti-IMD18, Anti-T3E, Anti-TCRE

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Produit recombinant

expressed in proprietary host

Conjugué

unconjugated

Forme d'anticorps

tissue culture supernatant

Type de produit anticorps

primary antibodies

Clone

SP7, monoclonal

Espèces réactives

human (tested)

Réactivité de l'espèce (prédite par homologie)

pig, rat, dog, bovine, rabbit, chicken

Technique(s)

flow cytometry: 1:100
immunoblotting: 1:25
immunohistochemistry: 1:150

Isotype

IgG

Numéro d'accès UniProt

P07766

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CD3E(916)

Description générale

This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells. It stains human T cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues. This antibody is suitable for staining normal and neoplastic T cells in formalin-fixed, paraffin-embedded tissues.

Immunogène

Synthetic peptide corresponding to internal region of the epsilon chain of human CD3 protein.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Vikrant Rai et al.
Scientific reports, 10(1), 15167-15167 (2020-09-18)
Cells of the immune system are present in the adult cochlea and respond to damage caused by noise exposure. However, the types of immune cells involved and their locations within the cochlea are unclear. We used flow cytometry and immunostaining
Yongfeng He et al.
Cell reports. Medicine, 2(9), 100392-100392 (2021-10-09)
Thymic carcinoma is rare and has a poorer prognosis than thymomas. The treatment options are limited after failure of platinum-based chemotherapy. We previously performed a single-center phase II study of pembrolizumab in patients with advanced thymic carcinoma, showing a 22.5%
Paul D Simonson et al.
Communications biology, 5(1), 627-627 (2022-06-27)
Multiparametric imaging allows researchers to measure the expression of many biomarkers simultaneously, allowing detailed characterization of cell microenvironments. One such technique, CODEX, allows fluorescence imaging of >30 proteins in a single tissue section. In the commercial CODEX system, primary antibodies
Filippos T Charitidis et al.
In vivo (Athens, Greece), 35(4), 1985-1997 (2021-06-29)
The pathway of initiation of psoriasis comprises the differentiation and infiltration of T-helper 17 (Th17) cells into the skin, characterized by the production of interleukin 17A and 17F (IL-17A/IL-17F) among other cytokines, resulting in a downstream cascade of events. Due
Xue Wu et al.
Cancer science, 112(11), 4444-4456 (2021-08-13)
WEE1 plays an important role in the regulation of cell cycle G2/M checkpoints and DNA damage response (DDR). Inhibition of WEE1 can increase the instability of the genome and have anti-tumor effects in some solid tumors. However, it has certain
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