SAB4504671

Anti-phospho-DDR1 (pTyr⁵¹³) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-CAK, Anti-CD167, Anti-DDR, Anti-EDDR1, Anti-HGK2, Anti-MCK10, Anti-NEP, Anti-NTRK4, Anti-PTK3, Anti-RTK6, Anti-TRKE
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 101 kDa
• Espèces réactives: rat, mouse, human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: Q08345
• Numéro d'accès UniProt: Q08345
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pTyr513)
• Informations sur le gène: human ... DDR1(780)

Description

Description générale

Discoidin domain receptor I (DDR1) is a receptor tyrosine kinase (RTK)/collagen-activated tyrosine kinase, that is located on human chromosome 6p21.

Immunogène

The antiserum was produced against synthesized peptide derived from human DDR1 around the phosphorylation site of Tyr513.

Immunogen Range: 479-528

Actions biochimiques/physiologiques

Discoidin domain receptor I (DDR1) plays important roles in several cancers. In renal cancer cells, DDR1 promotes epithelial to mesenchymal transition. It also increases invasion and metastasis of gastric cancer through epithelial-mesenchymal transition.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable