SAB4501900

Anti-MMP-13 antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Collagenase 3, MMP-13, MMP13, Matrix metalloproteinase-13
• Numéro MDL: MFCD03455405
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 53 kDa
• Espèces réactives: human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P45452
• Numéro d'accès UniProt: P45452
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... MMP13(4322)

Description

Description générale

Anti-MMP-13 Antibody detects endogenous levels of total MMP-13 protein.

Matrix metalloproteinases (MMPs) are a class of extra-cellular and membrane-bound proteases. MMP13 (matrix metallopeptidase 13) is mapped to human chromosome 11q14.3–23.2.

Immunogène

The antiserum was produced against synthesized peptide derived from human MMP-13.

Immunogen Range: 10-59

Actions biochimiques/physiologiques

MMP13 (matrix metallopeptidase 13) participates in tissue remodeling, inflammation, cytokine secretion and activation. It also plays an important role in acute lung injury, viral infections and chronic obstructive pulmonary disease. Mutation in MMP13 results in spondyloepimetaphyseal dysplasia, missouri type (SEMDMO).

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable