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SAB4200680

Sigma-Aldrich

Anti-Biotin antibody, Mouse monoclonal

clone BN-34, purified from hybridoma cell culture

Synonyme(s) :

Monoclonal Anti-Biotin antibody produced in mouse, Bios II, Coenzyme R, D-Biotin, Vitamin B7, Vitamin H

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

200

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

BN-34, monoclonal

Forme

buffered aqueous solution

Espèces réactives

canine, human, bovine, rat, mouse

Concentration

~1 mg/mL

Technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: 0.15-0.3 μg/mL
western blot: suitable

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Description générale

Biotin is a bi-heterocyclic, essential water soluble vitamin and a cofactor synthesized in most of the plants and prokaryotes. Protein-bound biotin in usually found in dietary sources like meat, cereals, egg yolk, liver and some vegetables.

Immunogène

biotinylated KLH

Actions biochimiques/physiologiques

Biotin functions as a coenzyme for acetyl CoA, pyruvate, propionyl-CoA and 3-methylcrotonyl-CoA carboxylases for the regulation of gluconeogenesis, lipid homeostasis, pleotropic gene expression and to replenish the intermediates of tricarboxylic cycle. Biotin bound to histones plays an important role in chromatin remodeling, DNA repair and repression of transposons to maintain genome stability. Inadequate biotin levels may lead to dermatitis, conjunctivitis, alopecia, and central nervous system abnormalities.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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