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Key Documents

S9399

Sigma-Aldrich

Staphylococcal enterotoxin A

from Staphylococcus aureus, lyophilized powder, enterotoxin

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352200
Nomenclature NACRES :
NA.77

product name

Staphylococcal enterotoxin A from Staphylococcus aureus,

Contient

sodium phosphate buffer as balance

Niveau de qualité

Composition

Protein, ~10% Lowry

Disponibilité

not available in USA

Impuretés

Staphylococcal enterotoxin B (SEB), essentially free

Solubilité

H2O: complete 1 mg/ml, clear, colorless

Température de stockage

2-8°C

Description générale

Staphylococcal enterotoxin A belongs to the family of staphylococcal exotoxins. It is secreted by Staphylococcus aureus, a Gram-positive bacteria.

Application

Staphylococcal enterotoxin A from Staphylococcal aureus was injected peritoneally in mice to induce sepsis.10
Staphylococcal enterotoxin A from Staphylococcus aureus has been used as an external standard in for the verification of TRANSIA assay kit, RIDASCREEN assay kit and Vidas Set 2 method. For in vitro toxin stimulation of mouse splenocytes.

Actions biochimiques/physiologiques

Staphylococcal enterotoxin A from Staphylococcus aureus is leading agent that causes of food poisoning. A concentration of as little as 0.5 mg/ml is sufficient to result in nausea, vomiting, diarrhea and cramps.8 It stimulates the cell proliferation of peripheral lymphocytes, induces the production of interferons and is important for gut immunity against S. aureus infections.9 It acts as a super antigen for T-lymphocytes.

Conditionnement

Package size based on protein content

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Marcin Kłak et al.
Scandinavian journal of infectious diseases, 42(5), 351-358 (2010-01-27)
Haemostatic balance shifts towards pro-coagulation during infection. Plasminogen, a key molecule of fibrinolysis, may play an important role in the pathogenesis of staphylococcal infections. In the present study, we assessed the impact of inhibition of plasminogen activation by tranexamic acid
Staphylococcal enterotoxin A (SEA).
L Spero et al.
Methods in enzymology, 78(Pt A), 331-336 (1981-01-01)
Hongshi Yu et al.
BMC genomics, 10, 416-416 (2009-09-08)
WNT4 is a critical signalling molecule in embryogenesis and homeostasis, but the elements that control its transcriptional regulation are largely unknown. This study uses comparative cross species sequence and functional analyses between humans and a marsupial (the tammar wallaby,Macropus eugenii)
Determination of staphylococcal enterotoxins in cheese by immunoenzyme assays
<BIG>Jankovic V, et al.</BIG>
Archives of Biological Sciences, 64, 1449-1454 (2012)
Dong Zhang et al.
Oncoimmunology, 9(1), 1744921-1744921 (2020-04-22)
T cell immunoglobulin and mucin domain-3 (TIM-3) is an immune checkpoint that regulates normal immune responses but can be exploited by tumor cells to evade immune surveillance. TIM-3 is primarily expressed on immune cells, particularly on dysfunctional and exhausted T

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